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Abstract #21262 Published in IGR 10-2
Analysis of 120 cases with primary open angle glaucoma in 6-year follow-up
Ai F-R; Li Y; Zhang X; Zhao J-LInternational Journal of Ophthalmology 2008; 8: 753-755
AIM: To obverse the long term changes of visual acuity, cup/disk ratio, intraocular pressure and visual field in patients with primary open angle glaucoma who are being treated. METHODS: A retrospective review of case series was performed on 120 patients (240 eyes) diagnosed as primary open angle glaucoma and treated in Peking Union Hospital from June 1994 to June 2000. There were 57 male (114 eyes) and 63 female (126 eyes), aged from 9 to 76 years old (mean age 46.5 years old). In 6 years follow up, visual acuity, cup/ disk ratio (C/D), intraocular pressure (IOP) with Goldmann applanation tonometer and visual field were measured in all patients. Visual field was tested using Humphrey 630 static perimeter, with program 24 - 2, 52 spots gray threshold map and 31.5 asb background light. The examination was carried out in half darkroom regularly, and the interval was less than 1 year. The visual field was divided into 4 quadrants, threshold stimulation sensitivity of every quadrant was calculated and statistic analysis was performed. RESULTS: Visual acuity declined every year, but it was tiny. Visual acuity of 1 year and 6 years after treatment were 0.84 ± 0.41, 0.94 ± 0.93 and 0.88 ± 0.32, 0.84 ± 0.29 respectively, and the differences were not statistically significant (P > 0.05). C/D increased during these years, especially in the last 3 years. The differences in C/D value between right eye and left eye were not statistically significant (P > 0.05) in the 1st, 2nd, 3rd, 4th year. In the 5th and 6th year, C/D value of the right and left eyes were significantly different compared with value of the 1st year (P < 0.05). IOP was controlled well in most patients, and there were significant differences before and after medication treatment. Visual acuity changes were diverse in different quadrants, and the inferior-temporal defect was marked (P < 0.05), differences between the 1st year and 2nd year and between the 1st year and the 6th year of the same quadrant were statistically significant (P < 0.05). CONCLUSION: Changes of visual field in primary open-angle glaucoma can indicate the extent of ocular damage, especially the progression of the disease, and can provide important evidences for treatment and prognosis. There are direct relations between disease control and changes of visual acuity, C/D ratio, IOP and visual field of the patient. LA: Chinese
Dr. Y. Li, Department of Ophthalmology, Peking Union Hospital, China Union Medical University, Beijing 100730, China. liyingpumch@sohu.com
Classification:
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)