advertisement
Abstract #21291 Published in IGR 10-2
Frequency of glaucoma in children with vernal conjunctivitis using steroids
Junejo SA; Laghari NA; Qazi AAJournal of the Liaquat University of Medical and Health Sciences 2007; 6: 8-12
OBJECTIVE: To determine the frequency of glaucoma in children with vernal conjunctivitis using topical steroids, referred to a tertiary eye care centre. DESIGN: Descriptive case series. SETTING: This study was carried out at department of Ophthalmology, Liaquat University Eye Hospital Hyderabad, Sindh - Pakistan, from July 2002 to December 2004 (Thirty months). PATIENTS AND METHODS: A total of 200 patients with chronic allergic conjunctivitis using topical steroids (Betamethasone, Dexamethasone, Prednisolone) for more than six months were examined. A thorough examination including visual acuity, Goldmann applanation tonometry, Schiot'z tonometry, Gonioscopy, slit lamp examination and dilated Ophthalmoscopy were performed. RESULTS: Out of 200 patients examined, fifteen (7.5%) were found having raised intraocular pressure (secondary glaucoma) due to prolonged use of topical steroids. The rise of intraocular pressure was bilateral in three patients (1.5%), and unilateral in twelve patients (6.0%). The topical steroids were discontinued. One patient with vernal conjunctivitis using topical steroids since more than two years developed left optic disc pallor with constriction of visual field, and posterior sub capsular cataract. The intraocular pressure was not controlled by ocular hypotensive agents, and glaucoma filtration surgery was advised. CONCLUSION: This study identifies the risk of intraocular pressure elevation in patients with allergic conjunctivitis, using topical steroids for longer periods. Long-term use of topical and systemic steroids produces secondary open-angle glaucoma similar to chronic simple glaucoma. We can conclude that Dexamethasone and Prednisolone are possible risk factors for producing glaucoma.
Dr. S.A. Junejo, Liaquat University Eye Hospital, Hyderabad, Sindh, Pakistan. Sameenafzal1@yahoo.com
Classification:
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
9.4.2.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.2 Glaucomas associated with disorders of the cornea, conjunctiva, sclera)
9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
