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Abstract #21319 Published in IGR 10-2
Detailed visualization of the anterior segment using fourier-domain optical coherence tomography
Asrani S; Sarunic M; Santiago C; Izatt JArchives of Ophthalmology 2008; 126: 765-771
OBJECTIVE: To study details of the anterior chamber drainage angle using Fourier-domain optical coherence tomography in healthy subjects and patients with angle abnormalities. METHODS: A high-speed anterior segment optical coherence tomography prototype was developed using a 1310-nm-wavelength swept light source. Six healthy subjects and 6 patients with glaucoma were imaged in an observational cross-sectional study. RESULTS: Schlemm's canal and the trabecular meshwork were visualized in all of the patients. Fifteen-millimeter scans enabled entire anterior segment visualization providing configuration details of the iris with respect to the angle. Four-millimeter scans permitted detailed views of the angle configuration and its structures. Volumetric imaging was possible and Schlemm's canal was visualized along part of its circumference. CONCLUSION: Anterior segment Fourier-domain optical coherence tomography permits detailed noncontact imaging of the angle and its structures, providing a tool to improve our understanding of the pathogenesis of narrow-angle glaucoma.
Dr. S. Asrani, Duke University Eye Center, Box 3802, Durham, NC 27710, USA. asran002@mc.duke.edu
Classification:
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
