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With the application of molecular biology in the ophthalmology, 11 chromosome sites, at least, have so far been identified as responsible for primary open angle glaucoma (POAG). In this article we reviewed the POAG-related genes, especially the three well-known virulence genes of MYOC, OPTN, WDR36, in terms of their locations, structures, functions, mutations, etc. LA: Chinese
Dr. B.-C. Ren, Department of Ophthalmology, School of Medicine of Xi'an Jiaotong University, Xi'an 710004 Shaanxi Province, China. rbc369@yahoo.com.cn
3.4.2 Gene studies (Part of: 3 Laboratory methods > 3.4 Molecular genetics)