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BACKGROUND AND OBJECTIVE: To examine the hypothesis that patients with increased central corneal thickness may have an overestimation of Goldmann applanation tension and a predisposition to hypotony-related complications. PATIENTS AND METHODS: A case-control analysis of patients with an intraocular pressure of 7 mmHg or less on two consecutive postoperative visits following glaucoma filtration or drainage implant surgery was performed. Forward stepwise multiple logistic regression was used to determine the model that best predicted hypotony-related complications defined as choroidal effusion or hypotony maculopathy. RESULTS: Forty-three eyes (17 with hypotony-related complications and 26 controls) of 43 patients were enrolled. Eyes with pseudophakia (P = .006) and lower postoperative intraocular pressure (P = .013) were significantly more likely to develop hypotony-related complications. Mean central corneal thickness was similar in eyes with hypotony-related complications (519 ± 32 μm) and controls (525 ± 37 μm) and was not a significant predictor of hypotony-related complications in the multivariate model (P = .90). CONCLUSION: Increased central corneal thickness does not represent a risk factor for hypotony-related complications following glaucoma surgery.
Dr. D.S. Greenfield, Bascom Palmer Eye Institute, 7101 Fairway Drive, Palm Beach Gardens, FL 33418, USA