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Abstract #22127 Published in IGR 10-4
Oral niacin can increase intraocular pressure
Tittler EH; De Barros DSM; Navarro JBVK; Freitas DGJ; Gheith ME; Siam GA; Spaeth GLOphthalmic Surgery Lasers and Imaging 2008; 39: 341-342
The intraocular pressure of a 73-year-old man with a history of primary open-angle glaucoma had been approximately 21 and 17 mmHg in the right and left eyes, respectively, while taking latanoprost 0.005% and dorzolamide hydrochloride 2%. When taking 500 mg of oral niacin (also known as vitamin B3 or nicotinic acid), his intraocular pressure increased to 37 and 27 mmHg in the right and left eyes, respectively, on one occasion. On reexamination, the intraocular pressure had increased to 28 and 23 mmHg in the right and left eyes, respectively. Each time the niacin was stopped, the intraocular pressure decreased to the original levels.
Dr. G.L. Spaeth, 840 Walnut Street, Philadelphia, PA 19107, USA