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Abstract #22336 Published in IGR 10-4
The effect of pneumatic trabeculoplasty on intraocular pressure: The results of a 6-month, open-label, multicenter study
Fogagnolo P; Rossetti L; Marchini G; Marraffa M; Rolando M; Ciancaglini M; Calabria G; Mastropasqua L; Orzalesi NEuropean Journal of Ophthalmology 2008; 18: 922-928
PURPOSE. To evaluate the effects of pneumatic trabeculoplasty (PNT) in ocular hypertension and glaucoma subjects. METHODS. A total of 63 consecutive subjects, either treated (79%) or untreated (21%), with intraocular pressure (IOP) between 20 and 25 mmHg were enrolled; the eye with higher IOP (or, in case of identical IOP, worse visual field) was treated with PNT, with the fellow eye used as control. Subjects underwent a baseline evaluation the day before treatment, two PNT treatments at day 0 and 7, visits at day 1, 8, 14, and at each month until the end of the study, which lasted 6 months. Safety was addressed at all visits; an IOP curve (at 8 and 10 a.m., 2 and 4 p.m.) was obtained at baseline and during monthly visits. RESULTS. In PNT eyes, baseline IOP was 22.2 ± 1.6 mmHg. Following PNT a statistically significant reduction of IOP occurred at all visits (p < 0.0001), with a mean decrease ranging from -2.7 ± 2.5 (-11.9 ± 10.8%) to -3.6 ± 2.6 mmHg (-16.0 ± 11.6%); mean reduction was 12.8 ± 11.5%. Although IOP diminished also in the control eyes after baseline (p < 0.05), the change in IOP was significantly higher in PNT group at each visit (p < 0.05). Mild side effects were experienced by 76% of subjects and they all resolved without sequelae. CONCLUSIONS. The results suggest the effect of this procedure in reducing IOP in glaucoma and ocular hypertensive subjects.
Dr. G.B. Bietti, Foundation-IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Roma - Italy
