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Abstract #22430 Published in IGR 10-4
Glaucoma neuroprotection: How far is it from a dream to reality
Ge JZhonghua Yan Ke Za Zhi 2008; 44: 385-387
Although drugs, such as Memantine, Calpain, Erythropoietin, have demonstrated exciting results for neuroprotection in laboratories, the phase III clinical trial of Memantine failed to prove such activity. So far, none of the neuroprotection drugs has been approved by FDA for clinical use with the failure of Memantine clinical trail indicating that the gap between basic science research and clinical application in glaucomatous optic neuroprotection remains to be filled. This paper offers a new insight into the field of neuroprotecion in glaucoma. To make the dream of optic neuroprotection reality, we have to implement new perspective strategies to integrate technologies and findings from the researches of human genomonics, proteomics, stem cells, and gene-transferred animal models. LA: Chinese
