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Abstract #22438 Published in IGR 10-4
Prevalence of exfoliation syndrome in central Sri Lanka: The Kandy Eye Study
Rudkin AK; Edussuriya K; Sennanayake S; Senaratne T; Selva D; Sullivan TR; Casson RJBritish Journal of Ophthalmology 2008; 92: 1595-1598
AIMS: To report the prevalence and correlates of exfoliation syndrome (XFS) in central, rural Sri Lanka. METHODS: A population-based, cross-sectional ophthalmic survey of inhabitants 40 years of age and over from villages in the Kandy District was conducted. Selection was randomised using a cluster sampling process. 1721 eligible participants were identified, 1375 participated. A detailed ophthalmic history and examination including ocular biometry was made of each participant. RESULTS: The prevalence of XFS was estimated to be 1.1% (95% CI 0.5 to 1.5%; 22 eyes). XFS was bilateral in eight subjects, unilateral in six subjects. Univariate analysis demonstrated a significant association between XFS and increasing age (p < 0.001), increasing intraocular pressure (odds ratio 1.2; 95% CI 1.09 to 1.27; p < 0.001), nuclear cataracts (odds ratio 1.92; 95% CI 1.47 to 2.51; p < 0.001), visual impairment (odds ratio 9.72; 95% CI 3.01 to 31.44; p < 0.001) and a history of hypertension (odds ratio 3.89; 95% CI 1.14 to 13.16; p = 0.030). CONCLUSION: XFS in this Sri Lankan population was associated with advanced age, raised intraocular pressure, nuclear cataracts, hypertension and visual impairment.
Dr. A.K. Rudkin, South Australian Institute of Ophthalmology, Adelaide, 5000, South Australia, Australia. adam@rudkin.com.au