advertisement
Abstract #22617 Published in IGR 11-1
Blood flow in the peripapillary retina in exfoliation glaucoma
Harju M; Kurvinen L; Saari J; Vesti EClinical and Experimental Ophthalmology 2008; 36: 738-743
PURPOSE: The aim of this article is to study peripapillary retinal blood flow in patients with progressive and stable exfoliation glaucoma (ExG). METHODS: Fifty-eight eyes with ExG were included; 25 of them had progressive and 33 stable glaucoma. Retinal blood flow in the peripapillary retina was measured with scanning laser Doppler flowmetry. Acquired flow maps were analysed with the automatic full-field perfusion image analyser. Multiple logistic regression was used to model progression of glaucoma. RESULTS: Mean retinal flow (MF; correlation coefficient, P-value; R = 0.36, P = 0.006) and retinal minimum diastolic flow (R = 0.33, P = 0.011) were positively correlated with visual field mean defect (MD). Factors associated with progressive glaucoma were mean intraocular pressure (OR = 1.198 for each mmHg; P = 0.050) and visual field MD (OR = 1.134 for each dB; P = 0.013). Age (P = 0.35), MF (P = 0.58), or presence of cardiovascular disease (P = 0.17) were not associated with glaucoma progression. CONCLUSION: No difference in peripapillary retinal blood flow between progressive and stable ExG could be found.
Dr. M. Harju, Helsinki University Eye Hospital, Helsinki, Finland. Mika.harju@aad.fi
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
