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Abstract #22625 Published in IGR 11-1
Secondary elevated IOP and cataracts after high-dose intravitreal triamcinolone and photodynamic therapy to treat choroidal neovascularization
Ruiz-Moreno JM; Montero JA; Amat P; Lugo FLJournal of Glaucoma 2009; 18: 69-72
PURPOSE: To analyze the appearance and evolution of high intraocular pressure (IOP) and cataracts after high-dose intravitreous triamcinolone acetonide (TA) and photodynamic therapy (PDT) to treat choroidal neovascularization associated with age-related macular degeneration. PATIENTS AND METHODS: Retrospective, consecutive, nonrandomized, interventional case series. Fifty-one consecutive eyes with subfoveal (all types) choroidal neovascularization associated to age-related macular degeneration were treated by PDT and intravitreal 19.4±2.1 mg/0.1 mL TA. Changes in IOP and lens were considered as primary outcome indicators. Optic disk changes were also considered. RESULTS: Twenty nine of 49 eyes (59%) needed topical therapy for high IOP at month 12, and 11 of 47 (23%) at month 24. Cataracts appeared in 14 of 42 phakic eyes (33%) after 12 months follow-up and in 22 of 40 phakic eyes (55%) completing 24 months follow-up. One eye showed an increased cup-to-disk ratio. CONCLUSIONS: The use of high-dose intravitreal TA is associated with cataracts and IOP elevation in approximately 50% of cases. The need for topical treatment for high IOP decreases during the second year.
Dr. J.M. Ruiz-Moreno, Department of Ophthalmology, Albacete Medical School, Castilla La Mancha University, Albacete, Spain. Jm.ruiz@umh.es
Classification:
9.4.5.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous)
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)