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Abstract #22773 Published in IGR 11-1
Ultrastructure of the endothelium of the drainage system of the eye
Kuleshova ON; Nepomnyashchikh GI; Aidagulova SV; Shvedova EVBulletin of Experimental Biology and Medicine 2008; 145: 634-637
The endothelium of the ocular drainage system (Schlemm's canal, collector tubules, and aqueous veins) in primary juvenile glaucoma undergoes degenerative dystrophic changes with compensatory hypertrophy and proliferation at the initial stages of the glaucomatous process and atrophy and desquamation at advanced and terminal stages. Progressive decrease in the pinocytous function of endotheliocytes, reduction of the protein-synthesizing and mitochondrial compartments of the cytoplasm, and formation of autophagosomes reflect the process of endotheliocyte degeneration in general.
Dr. O.N. Kuleshova, Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia. pathol@soramn.ru
Classification:
2.5.2 Schlemms canal (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
2.5.3 Scleral outlet channels (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
3.2 Electron microscopy (Part of: 3 Laboratory methods)
