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Abstract #23007 Published in IGR 11-1
Clinical analysis of the parameters detected by HRT-II and Humphrey perimetry in the new international classification of angle-closure glaucoma
Yang X-G; Guo B; Liu Z; Yu J-N; Li P; Liu J-R; Li H-M; Ma Q-LInternational Journal of Ophthalmology 2008; 8: 2239-2243
AIM: To study the visual field defects with Humphrey perimetry and the optic disc parameters of HRT in patients classified with the international angle-closure glaucoma classification, and to analyze the relationship among the HRT-II parameters and mean defect (MD). METHODS: Totally 117 eyes of 69 patients were divided into 3 groups: primary angle-closure suspect (PACS, 38 eyes), primary angle-closure (PAC, 53 eyes) and primary angle-closure glaucoma (PACG, 26 eyes) according to the international angle-closure glaucoma classification method. Sixty eyes of 30 volunteers without eye diseases and the above 117 eyes were examined by HRT-II and Humphrey Field Analyzer, and cup area (CA), disk area (DA), rim area (RA), cup volume (CV), rim volume (RV), cup/disk area ratio (CDAR), linear cup/disk ratio (LCDR), mean cup depth (MCD), maximum cup depth (max CD), cup shape measure (CSM), height variation contour (HVC), mean RNFL thickness (MRNFLT), RNFL cross sectional area (RCSA) and mean defect (MD) values were obtained from the report papers. The differences of parameters between normal eyes and glaucoma eyes in 3 groups and the relationship among MD and HRT-II parameters in each group were analyzed with statistic software. RESULTS: Among the normal volunteer group and PACS, PAC, PACG group, there were significant differences of parameters of HRT-II and MD value of Humphrey perimetry (P < 0.01). The regression analysis showed that a linear relationship existed between LCD and MD in normal eyes, among DA, CA and MD in PACS group, and among CA, RA, CV, CDAR, HVC and MD in PAC group. With a multiple sieving stepwise regression method, CV and HVC were selected for 2 variables in the regression equation. The Pearson correlation coefficients between CV, HVC and MD were 0.290 and 0.301 in PAC group, respectively, and the regression equation was Y=4.475 X(1) + 5.338 X2 - 0.480, where Y was MD, X(1) was CV and X2 was HVC. CONCLUSION: There are clinical values of HRT-II and Humphrey perimetry in the new international classification of angle-closure glaucoma, and the cross-reference analysis between MD and CV, HVC may be helpful to evaluate the development of PACG. LA: Chinese
Dr. X.-G. Yang, Shaanxi Ophthalmic Medical Center, Fourth Hospital of Xi'an City, Xi'an 710004 Shaanxi Province, China. yangxinguang62@hotmail.com
Classification:
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.9.1.1 Confocal Scanning Laser Ophthalmoscopy (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
