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Abstract #23380 Published in IGR 11-1
Ocular perfusion pressure and glaucoma: the Beijing Eye Study
Xu L; Wang YX; Jonas JBEye 2009; 23: 734-736
PURPOSE: IThe purpose of the study was to examine a relationship between ocular perfusion pressure and open-angle glaucoma in a population-based setting in China. METHODS: The Beijing Eye Study 2006 is a population-based investigation, which included 3251 subjects (response rate: 73.2%). Mean age was 60.4±10.0 years (range, 45-89 years). Glaucoma was defined by a glaucomatous appearance of the optic disc. RESULTS:Neither in univariate nor in multivariate statistical analysis, systolic blood pressure, diastolic blood pressure, mean blood pressure, and ocular perfusion pressure were significantly associated with the prevalence of open-angle glaucoma. It also holds true if the whole glaucoma group was differentiated into a normal-pressure glaucoma group and a high-pressure glaucoma group. CONCLUSIONS: In contrast to earlier population-based studies on western societies, the prevalence of open-glaucoma (also when differentiated into normal-pressure and high-pressure glaucomas) was not associated with the ocular perfusion pressure. The reasons for the discrepancy may be that most of the glaucoma patients in this study were untreated; that more than 80% of the glaucoma subjects of the present investigation had an intraocular pressure measurement <22 mmHg; and differences in the definition of glaucoma.
Dr. L. Xu, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
1.1 Epidemiology (Part of: 1 General aspects)