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Abstract #23494 Published in IGR 11-2
Models of glaucoma in rodent animal
Fan H; Ni WChinese Ophthalmic Research 2009; 27: 243-246
Glaucoma is a heterogeneous group of optic neuropathies that shares a similar set of clinical features including optic nerve atrophy and progressive loss of visual field and further results in blindness. To establish suitable animal model is an useful approach to elucidate the etiology and pathology of glaucoma as well as developing novel and more effective therapies. Rodent model of glaucoma has recently become popular as research tool because it is easy to be reformed by transgenic technology and very similar to people' constitution. The modeling method of glaucoma in recent years was reviewed in two aspects;intraocular hypertension and normal intraocular tension. LA: Chinese
H. Fan. Department of Ophthalmology, Third People' S Hospital Affiliated, Shanghai Jiaotong University, Shanghai 20190, China.
Classification:
5.1 Rodent (Part of: 5 Experimental glaucoma; animal models)