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AIM: To monitor intraocular pressure (IOP) fluctuation change in healthy young with PASCAL dynamic contour tonometer (DCT) and KEELER non-contact tonometer (NCT) and to compare the measuring results with the two methods. METHODS: Prospective study including 54 eyes of 27 healthy young with DCT and another 168 eyes of 84 healthy young with NCT for 24 hours. All the healthy young are aged from 19 to 22, and every two hours should be a time interval. IOP was measured from 08: 00 am to next day 06: 00am. The measurement at each time was repeated three times with the two methods and the mean value was taken into account. RESULTS: The mean values were in DCT and NCT were 15.76 (plus or minus) 2.37 mmHg and 13.77 (plus or minus) 4.33 mmHg. The maximum mean IOP in DCT group appears at 08: 00am and the minimum at 08: 00pm, while the maximum mean IOP in NCT group appears at 06: 00am and the minimum at 10: 00pm. The fluctuations of binocular IOP were 4.56 (plus or minus) 1.19mmHg and 4.12 (plus or minus) 1. 21 mmHg in left and right eyes in DCT group, while were 4.71 (plus or minus) 2.23mmHg and 5.00 (plus or minus) 1.50mmHg in NCT group. There was no significant difference in the mean IOP between different genders (F= 1.459, P = 0. 229) and both eyes (F = 0. 668, P = 0. 451) by the two methods. Variance in 24 hours had statistical significance (F = 64. 407, P = 0. 000), and the trend is a hyperbola. Tendency of variance with the change of time between the two methods has statistical significance (F= 16.615, P = 0. 000). CONCLUSION: IOP in healthy young shows a circadian change, where lowest point comes at the end of daylight, while the highest at the end of night. Tendency of circadian variation and measured values at each situs recorded from different measurements have significant difference. IOP readings are higher at majority situs with DCT than NCT. For routine clinical use, it should take note of the differences of measuring time and methods, when IOP is taken as the reference to evaluate the diagnosis and treatment for primary glaucoma. LA: Chinese
Z.-M. Zhang. Air Pro Teaching and Research, Department of Aerospace Medicine, The Fourth Military Medical University, Xi'an 710032 Shaanxi Province, China. Zhangzm@fmmu.edu.cn
6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
6.1.2 Fluctuation, circadian rhythms (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)