advertisement
Abstract #23612 Published in IGR 11-2
Clinical significance of pattern electroretinogram and retinal nerve layer thickness in the early diagnosis of glaucoma
Wang Y; Chen H-J; Zhu L; Wu R; Wang WInternational Journal of Ophthalmology 2009; 9: 478-480
AIM: To measure retinal nerve fiber thickness method by the diagnostic value of the pattern electroretinograms (PERG), the pattern visual evoked potentials (PVEP) and optical coherence tomography (OCT). And it's clinical significance in primary open angle glaucoma (POAG) and normal-tension glaucoma in the early diagnosis (NTG). METHODS: Thirty-six cases (72 eyes) with early and advance glaucoma, including primary open angle glaucoma in 22 cases (44 eyes), normal-tension glaucoma 14 cases (28 eyes) for PERG, PVEP and OCT and vision inspection. And statistical analyse test results and, paired comparison of X(2) test method of examination in early diagnosis of glaucoma sensitivity. RESULTS: PERG and PVEP difference was significant (P < 0.01), PERG and OCT difference was significant (P < 0.01) PVEP and OCT was no significant difference. PERG, PVEP and OCT examination in the early days of the abnormal rate of glaucoma were 80%, 37% and 33%. CONCLUSION: The sensitivity of PERG is higher than those of OCT or PVEP in early diagnosis of glaucoma. The PERG combined with quantification of RNFL thickness by OCT may be more helpful to early diagnosis of glaucoma. But PERG may be subject to many factors in the diagnosis of other diseases. But the OCT examination of the fundus has its specificity. So it has clinical significance to unite so many kinds of examination methods for early diagnosis of glaucoma and monitoring. LA: Chinese
Y. Wang. Department of Ophthalmology, Huadong Hospital, Shanghai 200040, China. w.y.2006@hotmail.com
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
