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(3) 15 Miscellaneous (27)

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Abstract #23629 Published in IGR 11-2

Effect of tribulus terrestris L. on the retinal ganglion cells

Liao M-Y; Huang L-N; Zeng P; Liu J
International Journal of Ophthalmology 2009; 9: 282-283

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AIM: To observe the effect of tribulus terrestris L. (TTL) on the retinal ganglion cells (RGCs) with experimental hyper-intraocular pressure(HIOP). METHODS: Sixteen healthy NZ rabbits were randomly divided into 3 groups: normal group (A); HIOP group (B); HIOP treatment group (C). HIOP was induced by 20g/L methylcellulose injection into the anterior chamber with HIOP group. Treatment group was injected 5 mg/kg TTL every day. After 30 days, the rabbits' globes were removed for RGCs observed by light microscopy,and the thickness of retina layer was examined. RESULTS: Hyper-intraocular pressure occurred in all of rabbits, the degeneration of RGCs and the retinal nerve fiber layer in the C group was lower than those in the B group. CONCLUSION: TTL. may protect RGCs in some extent. LA: Chinese

M.-Y. Liao. Hubei College of Traditional Chinese Medicine, Wuhan 430061 Hubei Province, China. lmy280@163.com

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Classification:

15 Miscellaneous
5.3 Other (Part of: 5 Experimental glaucoma; animal models)
11.8 Neuroprotection (Part of: 11 Medical treatment)

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