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Abstract #23639 Published in IGR 11-2
Clinical study on corneal endothelial changes after phacoemulsification in eyes with primary angle-closure glaucoma
Pang R-H; Tang G-XInternational Journal of Ophthalmology 2009; 9: 306-308
AIM: To compare the changes of corneal endothelial cell density before and after phacoemulsification and trabeculectomy treating the patients with primary angle-closure glaucoma. METHODS: Totally 133 patients with primary angle-closure glaucoma and coexisting cataract were randomly divided into two groups. Phacoemulsification and trabeculectomy were performed respectively. The endothelium cell density, average cell area and percentage of hexagonal cell density were determined by Bio-optics LSM 22000 CS corneal specula microscope preoperatively and 3 months postoperatively. The endothelial images were analyzed by computer. RESULTS: There were significant differences in IOP reduction in two groups before and after surgery (P < 0.01). The density of corneal endothelial cells changed from per mm(2) 2 483 (plus or minus) 486 to 2 336 (plus or minus) 305 in phaco group and from per mm(2) 2 458 (plus or minus) 375 to 2 326 (plus or minus) 216 in Trab group with no signifant differences. There were no significant differences in cell perimeter, average cell area, cell density, and polymegathism in two groups. The percentage of hexagonal cell density was decreased in patients with shallow anterior chamber (P < 0.05). CONCLUSION: Phacoemulsification is a safe and effective treatment to PACG. It is important to check the density of corneal endothelial cells before surgery. LA: Chinese
R.-H. Pang. Department of Ophthalmology, Xingtai Eye Hospital, Xingtai 054001 Hebei Province, China. runhuipang@yahoo.com.cn
Classification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
9.3.2 Chronic primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
12.12.3 Phacoemulsification (Part of: 12 Surgical treatment > 12.12 Cataract extraction)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
