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Abstract #23641 Published in IGR 11-2
Changes of color pattern reversal visual evoked potential of primary glaucoma
Wang P-B; Tong Y; Xia Z-H; Tan Q; Xia X-BJournal of Central South University. Medical sciences 2008; 33: 821-825
OBJECTIVE: To investigate the changes of color pattern reversal visual evoked potential (CPR-VEP) of primary glaucoma using different temporal frequencies, and to search for the best temporal frequency parameters and color parameters. METHODS: Vision Monitor visual electrophysiograph (Metrovision, France) was used to record CPR-VEP at different temporal frequencies (1, 2, 4, 8, 16, and 32 Hz) and different color stimulations (black / white, red / green, blue / yellow) in 41 cases (70 eyes) with primary glaucoma (glaucoma group) and 13 normal subjects (26 eyes) (normal control group). P(100) wave amplitudes were compared. RESULTS: (1) In the normal control group, P(100) amplitudes declined while the temporal frequency of black / white stimulation was increasing, but they had peaks at 2 Hz and 8 Hz red / green stimulation and blue / yellow stimulation. (2) In the glaucoma group, CPR-VEP P(100) declined while temporal frequency was increasing under 3 color stimulations, but had a peak at 8 Hz. Af 2 Hz -16 Hz, P (100) amplitudes were related with the mean defect of Humphrey visual field, especially with all 3 color stimulatins at 8 Hz and with blue / yellow stimulation at 2 Hz and 16 Hz. (3) P(100) amplitude was most different under the 3 color stimulations between the 2 groups at 8 Hz. CONCLUSION: The changes of CPR-VEP P(100) amplitude can objectively reflect the glaucoma visual function damage. CPR-VEP P(100) amplitude has certain value in studying glaucoma under different color stimulations (black / white, red / green, blue / yellow ) at 8 Hz, and blue / yellow stimulation at 2 Hz and 16 Hz. LA: Chinese
P.-B. Wang. Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China. pingbao-wang@hotmail.com
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)