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Abstract #23672 Published in IGR 11-2
A method to detect progression of glaucoma using the multifocal visual evoked potential technique
Wangsupadilok B; Greenstein VC; Kanadani FN; Grippo TM; Liebmann JM; Ritch R; Hood DCDocumenta Ophthalmologica 2009; 118: 139-150
PURPOSE: To describe a method for monitoring progression of glaucoma using the multifocal visual evoked potential (mfVEP) technique. METHODS: Eighty-seven patients diagnosed with open-angle glaucoma were divided into two groups. Group I, comprised 43 patients who had a repeat mfVEP test within 50 days (mean 0.9 ± 0.5 months), and group II, 44 patients who had a repeat test after at least 6 months (mean 20.7 ± 9.7 months). Monocular mfVEPs were obtained using a 60-sector pattern reversal dartboard display. Monocular and interocular analyses were performed. Data from the two visits were compared. The total number of abnormal test points with P < 5% within the visual field (total scores) and number of abnormal test points within a cluster (cluster size) were calculated. Data for group I provided a measure of test-retest variability independent of disease progression. Data for group II provided a possible measure of progression. RESULTS: The difference in the total scores for group II between visit 1 and visit 2 for the interocular and monocular comparison was significant (P < 0.05) as was the difference in cluster size for the interocular comparison (P < 0.05). Group I did not show a significant change in either total score or cluster size. CONCLUSION: The change in the total score and cluster size over time provides a possible method for assessing progression of glaucoma with the mfVEP technique.
Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
