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Abstract #23733 Published in IGR 11-2

Functional properties of fibronectin in the trabecular meshwork

Faralli JA; Schwinn MK; Gonzalez JM Jr; Filla MS; Peters DM
Experimental Eye Research 2009; 88: 689-693

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Fibronectin plays a number of important roles in the extracellular matrix (ECM) including providing structural support and signaling cues for cell survival, migration, differentiation, gene expression, growth factor signaling, and cell contractility. In this review, we examine recent findings about the biological and structural properties of fibronectin and discuss how these properties could contribute to the regulation of aqueous humor (AH) outflow in the trabecular meshwork (TM).

Department of Pathology & Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706, USA.

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Classification:

2.5.1 Trabecular meshwork (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
3.6 Cellular biology (Part of: 3 Laboratory methods)

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