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Abstract #23765 Published in IGR 11-2
The Groningen Longitudinal Glaucoma Study. II. A prospective comparison of frequency doubling perimetry, the GDx nerve fibre analyser and standard automated perimetry in glaucoma suspect patients
Jansonius NM; Heeg GPActa Ophthalmologica 2009; 87: 429-432
PURPOSE: We aimed to determine prospectively the incidence of abnormal test results on frequency doubling perimetry (FDT), the nerve fibre analyser (GDx) and standard automated perimetry (SAP) in a cohort of glaucoma suspect patients with normal findings for all these tests at baseline. METHODS: Seventy glaucoma suspect patients were followed prospectively for 4 years with SAP (Humphrey field analyser 30-2 SITA Fast), FDT (C-20 full-threshold) and GDx (Version 2.010) in a clinical setting. All patients had normal baseline test results on SAP, FDT and GDx. After the follow-up period, the number of patients who converted (whose test results changed from normal at baseline to reproducibly abnormal during follow-up) were counted for each technique and then compared. The cut-off point for FDT was > 1 depressed test-point p < 0.01 in the total deviation probability plot; the cut-off point for GDx was the Number > 29. RESULTS: Of the 70 glaucoma suspect patients, three converted on FDT, 14 on GDx and six on SAP. These proportions are significantly different for GDx versus SAP (p = 0.033) and GDx versus FDT (p = 0.002), but not for FDT versus SAP (p = 0.256). CONCLUSIONS: The most frequent finding after a 4-year follow-up was conversion on GDx.
Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. n.m.jansonius@ohk.umcg.nl
Classification:
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.9.1.2 Confocal Scanning Laser Polarimetry (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
