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Abstract #23853 Published in IGR 11-2
Anterior ocular biometry using 3-dimensional optical coherence tomography
Fukuda S; Kawana K; Yasuno Y; Oshika TOphthalmology 2009; 116: 882-889
PURPOSE: To evaluate anterior ocular biometry by comparing the measurements of central corneal thickness (CCT) and anterior chamber depth (ACD) with 3-dimensional corneal and anterior segment optical coherence tomography (CAS-OCT) and other methods. DESIGN: Cross-sectional study. PARTICIPANTS: Forty eyes of 40 normal subjects. METHODS: The CCT was measured by 4 methods (CAS-OCT, Scheimpflug camera, scanning-slit topography, and ultrasonic pachymetry), and the ACD was measured by 3 methods (CAS-OCT, Scheimpflug camera, and scanning-slit topography). The anterior chamber volume (ACV) was calculated with CAS-OCT. Repeatability and reproducibility of CAS-OCT measurements were evaluated. MAIN OUTCOME MEASUREMENTS: The CCT and ACD were measured and compared between devices. The ACV was calculated with CAS-OCT. Coefficient of variation and intraclass correlation coefficient (ICC) were calculated to evaluate repeatability and reproducibility of CAS-OCT measurements. RESULTS: The mean CCT was 547.0±39.0, 590.0±39.8, 525.0±45.0, and 545.0±40.3 microm with CAS-OCT, Scheimpflug camera, scanning-slit topography, and ultrasonic pachymetry, respectively. Significant differences were observed among the 4 methods (P<0.0001; 1-way analysis of variance [ANOVA]). The CCT measured with Scheimpflug camera was significantly larger than those measured with the other methods (P<0.0001; Bonferroni multiple comparison), but there was no significant difference among the other 3 methods. The mean ACD was 3.01±0.47, 3.04±0.52, and 2.88±0.50 mm with CAS-OCT, Scheimpflug camera, and scanning-slit topography, respectively. There was no significant difference among the 3 methods (P = 0.678; 1-way ANOVA). A significant linear correlation in CCT and ACD were observed between CAS-OCT and other methods (all P<0.0001). The mean ACV calculated with CAS-OCT was 169.7±23.1 mm(3). The coefficient of repeatability and reproducibility of CCT and ACD measurements were <5% and ICCs were >0.98. CONCLUSIONS: The CCT measurements were comparable among CAS-OCT, ultrasonic pachymetry, and scanning-slit topography, but Scheimpflug camera yielded a significantly higher CCT value. There was no significant difference in ACD measurements among CAS-OCT, Scheimpflug camera, and scanning-slit topography. The ACV was noninvasively measured by CAS-OCT.
Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, Japan. Caesar.ShihTzu@gmail.com
Classification:
6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
6.8.1 Anterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
