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Abstract #23925 Published in IGR 11-2
Hyperfluorescence of the optic disc with indocyanine green angiography
Maaijwee K; van den Biesen PR; van Meurs JCEye 2009; 23: 819-821
PURPOSE: One-fourth of the patients with exudative age-related macular degeneration (AMD) treated with an autologous retinal pigment epithelium (RPE)-choroid translocation had a hyperfluorescent optic disc with indocyanine green angiography (ICGA). This study aimed to identify whether indocyanine green (ICG)-assisted surgery was related to the hyperfluorescence of the optic disc with ICGA. METHODS: Retrospective observational case series of 31 AMD patients treated with an RPE-choroid translocation and who had ICGA after surgery. The ICGAs were assessed for hypo/iso/hyperfluorescence of the optic disc and fluorescence was related to the time interval between ICGA and the possible use of intravitreal ICG. RESULTS: The optic disc was hyperfluorescent in six patients, isofluorescent in one, and hypofluorescent in 24 patients. All hyperfluorescent optic discs and 7 of the 24 hypofluorescent optic discs were preceded with ICG-assisted surgery with a time interval of 7±3 weeks and 43±12 weeks, respectively (P=0.001, Student t-test). The other 17 hypofluorescent discs were not preceded by ICG-assisted surgery and the one isofluorescent optic disc was observed 32 weeks after ICG-assisted surgery. CONCLUSION: There was a statistically significant correlation between intravitreal ICG use during surgery and a hyperfluorescent optic disc with ICGA in our patient group.
The Rotterdam Eye Hospital, Rotterdam, The Netherlands. kmaaijwee@hotmail.com
Classification:
6.10.2 Posterior segment (Part of: 6 Clinical examination methods > 6.10 Fluorescein (ICG) angiography)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
