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Abstract #24190 Published in IGR 11-3
The influence of eccentric scanning of optical coherence tomography on retinal nerve fiber layer analysis in normal subjects
Yoo C; Suh IH; Kim YYOphthalmologica 2009; 223: 326-332
See also comment(s) by Marco Vizzeri •
AIM: To investigate the influence of eccentric scanning on retinal nerve fiber layer (RNFL) analysis using Stratus optical coherence tomography (OCT) in normal Koreans when the eccentricity of scanning occurs in 4 different directions. METHODS: Thirty-one eyes of 31 persons underwent 1 concentric disk-centered and 4 superiorly, inferiorly, nasally and temporally eccentric RNFL OCT scans. RESULTS: The average RNFL thickness measured by temporally eccentric scanning (115.1 microm) was significantly greater when compared with that found by concentric scanning (107.1 µm; p < 0.0001). The proportions of eyes outside normal limits on the RNFL analysis map using the criterion of >or=1 clock hour abnormal at the <1% level in superiorly (12/31, 38.7%), nasally (16/32, 51.6%) and temporally (12/31, 38.7%) eccentric scans were significantly different in comparison with the concentric (4/31, 12.9%) scan (p < 0.05). CONCLUSION: An off-centered OCT scan affected RNFL thickness measurement and its interpretation. © 2009 S. Karger AG, Basel.
Dr. C. Yoo, Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea
Classification:
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)