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OBJECTIVE: and uninvasive advantages, visual evoked potential ( VEP ) is widely used in However,the present superposition averaging technique used in potential recording shows some limitations. The present was launched to compare the results between the auto-reference, auto-correlation and adaptation interference cancellation (AAA-ICM) and the superposition averaging technique in their application in signal extraction of pattern reversal visual potential(P-VEP) and to evaluate its clinical feasibility. Methods P-VEP of 40 patients with glaucoma and 33 healthy were recorded,and both the single extraction technique and superposition averaging technique were respectively employed collect the recording signals, and then the normal reference range for the latency of Pm wave was calculated. The single technique and superposition averaging technique were compared in respect to their signal extraction results in the group. Results The sensitivity, specificity and accuracy from single extraction technique was respectively 98.4%, 9% and 96. 3% in glaucoma group compared with the normal vlaue. The normal latency value of Pm wave was( 135. 75 ± 37)ms based on the two signal extraction techniques,and that of glaucoma patients was significantly prolonged in 52 eyes,but statistical significant difference was found in the latency of Pm between normal and glaucoma eyes (P >0. 05). Conclusion The results from the new single extraction technique was consistent with traditional superposition averaging technique during the of glaucoma, however, the new technique has some advantages such as less time, better tolerance and less background encephalo-signal than the conventional one. The present study indicates that the single extraction technique based on AAA-has great potential value in clinical practice. LA: Chinese
Dr. M. Zhao, Department of Ophthalmology, Affiliated First Hospital, Chongqing Medical University, Chongqing 400016, China. minzhao2002@yahoo.com.cn
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)