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Abstract #24393 Published in IGR 11-3
The relationship of intranasal steroids to intraocular pressure
Bergmann J; Witmer MT; Slonim CBCurrent Allergy and Asthma Reports 2009; 9: 311-315
Intranasal corticosteroids have become a gold standard in therapy for allergic rhinoconjunctivitis. A direct relationship between topical and systemic corticosteroids and elevated intraocular pressure (IOP) has been recognized for more than 50 years. However, this steroid-induced response is highly variable. Glaucoma is an eye disease caused by an increase in IOP and results in optic nerve cell death and vision loss. Intranasal corticosteroids are absorbed systemically albeit in small measurable amounts. Some studies suggest a relationship between intranasal steroids and increased IOP. Large prospective studies to determine if there is a significant relationship between intranasal steroids and increased IOP are lacking. We review the current knowledge base regarding intranasal steroid usage and steroid-induced glaucoma.
Dr. C.B. Slonim, Department of Ophthalmology, University of South Florida College of Medicine, 4444 East Fletcher Avenue, Tampa, FL 33613, USA. chuck@slonim.us
Classification:
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
