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Purpose Ocular blood flow is affected in several ocular pathological conditions, such as glaucoma. Despite this, the effects of reducing cardiac output on the perfusion of the optic nerve and its possible role in the pathogenesis of glaucoma in these patients are unknown. Then, we decided to evaluated alterations in color Doppler imaging of the ophtalmic artery in patietns with heart failure (HF). METHODS Doppler parameters of ophthalmic artery of 21 patients with heart failure were evaluated. These parameters were correlated with assessments by echocardiography, clinical status and changes of the optical disk. Finaly, they were compared with 21 controls without heart disease. RESULTS Nine men and 14 women with an average age of 50.7(plus or minus)11 years, ranging from 27 to 72 years were studied. Gender and age of cases compared with controls were similar (p=0.9 and p=1.0, respectively). The average diastolic velocity of the cases was lower than that of controls, and this difference was significant (p=0.01 and p=0.02, right and left eyes, respectively). There was a correlation between the resistivity index of the ophthalmic artery and the diastolic blood pressure of patients with HF (p=0.03 and p=0009, right and left eyes, respectively). The other studied parameters showed no statistical significance. There was low general correlation between the assessed Doppler parameters and changes in the optic disk. CONCLUSION Reduced diastolic velocity in ophthalmic artery of patients with heart failure compared with controls was demonstrated. This finding, in correlation with literature data, may precede the glaucoma and be related to its vascular pathogenesis in these individuals. The dyastolic blood pressure appears to be a good clinical parameter in the determination of cardiac patients at higher risk of developing changes in ocular microvasculature.
D. Freitas. Universidade Federal de sao Paulo, Unifesp/ EPM, Sao PauloBrazil.
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)