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Abstract #25408 Published in IGR 12-1
Correlation between ocular pulse amplitude and color Doppler flow imaging of the retro bulbar vessels in glaucoma
Mirkovic M; Marjanovic I; Mijajlovic MCerebrovascular Diseases 2009; 27: 13
Purpose: The aim of this study was to evaluate the correlation between ocular pulse amplitude, and Color Doppler Imaging of the retro bulbar vessels, in patients with normal tension glaucoma, ocular hypertension and glaucoma suspicious. Methods: 80 eyes of the 40 patients were examined. First group comprised 20 patients with normal tension glaucoma and second group included 20 patients with ocular hypertension and glaucoma suspicious, without any antiglaucomatous therapy. Ocular pulse amplitude was measured with the dynamic contour tonometer by one investigator; Color Doppler Imaging was performed by one investigator blinded to ophthalmologic diagnosis. Hemodynamic parameters were measured in Internal Carotid Artery (ICA), Ophthalmic Artery (OA), Central Retinal Artery (CRA), and Posterior Cilliary Arteries (PCA). Peak systolic (PSV), end-diastolic (EDV) velocities were measured; resistance (RI) and pulsatility index (PI) were calculated using ultrasound machine Aloka Alpha 10 7.5-10 MHz linear probe. Results: Spearman regression analysis showed direct correlation of OPA and PSV, EDV and PI in both groups, but indirect correlation in the RI of the ICA, RI and PI of the CRA in glaucoma. In the frst group, there was statistical signifcant correlation in RI of the CRA (r=+0.5; p=0.02), and border signifcance in RI of the ICA (r=+0.43; p=0.056). Conclusions: Increase of the OPA was mostly followed by the increase of the PSV, EDV, RI, and PI of the retro bulbar vessels in glaucoma. Color Doppler Imaging of the blood flow in retro bulbar vessels is valuable method in diagnosis of the vascular mechanism in optic neuropathy.
M. Mirkovic. Department of Neurology, Health Centre Valjevo, ValjevoSerbia.
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
