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Abstract #25469 Published in IGR 12-1
Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
Bagli E; Gartzios C; Asproudis I; Kitsos GClinical Ophthalmology 2009; 3: 297-305
Purpose: The comparison of one-site versus two-site phacotrabeculectomy in patients with pseudoexfoliation glaucoma (PEXG) and primary open-angle glaucoma (POAG), with respect to intraocular pressure (IOP), antiglaucomatous medication (AM) requirements and visual acuity (VA). Methods: Forty-seven patients (eyes) with cataract and POAG and 46 sex- and age-matched patients with cataract and PEXG were randomized to one- or two-site phacotrabeculectomy and reviewed with a follow-up at three years. Results: Mean preoperative IOP was 22.04 (plus or minus) 2.27 mmHg and 22.92 (plus or minus) 2.35 mmHg in POAG and PEXG groups (p > 0.05) using a mean of 2.76 (plus or minus) 0.74, 2.74 (plus or minus) 0.69 AM, respectively (p > 0.05). After three years of follow-up, the mean IOP was 15.04 (plus or minus) 1.57 mmHg in the one-site, 15.04 (plus or minus) 1.99 mmHg in the two-site group with POAG, 15 (plus or minus) 1.8 mmHg in the one-site, 15.32 (plus or minus) 1.31 mmHg in the two-site group with PEXG, using a mean of 0.68 (plus or minus) 0.69, 0.84 (plus or minus) 0.75, 0.96 (plus or minus) 0.67, and 0.8 (plus or minus) 0.62 AM, respectively. Mean IOP and AM postoperatively were significantly less compared to preoperatively for each group (p < 0.05). No difference was observed in mean IOP and AM between the four groups at three years postoperatively (p > 0.05). VA improved similarly in four groups at the three-year follow-up (p < 0.05). Intraoperative, postoperative complications, and need for 5-fluorouracil injections were similar between the surgical groups. Conclusion: One-site and two-site phacotrabeculectomy without the use of antimetabolites intraoperatively were similarly safe and effective in IOP control over a three-year follow-up period in patients with POAG and PEXG.
E. Bagli. Aravantinou 6a, 45444 Ioannina, Greece. elenibgl@hotmail.com
Classification:
12.14.3 Phacoemulsification (Part of: 12 Surgical treatment > 12.14 Combined cataract extraction and glaucoma surgery)
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
9.2.3 Open angle glaucoma with elevated IOP (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
