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Abstract #25599 Published in IGR 12-1
Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap
Hirooka K; Takagishi M; Baba T; Takenaka H; Shiraga FActa Ophthalmologica 2010; 88: 60-64
Purpose: To investigate the relationship between filtering bleb function and Stratus optical coherence tomography (OCT) images. Methods: We studied 72 eyes of 65 consecutive patients who had a fornix-based conjunctival flap in primary trabeculectomy with mitomycin C (MMC). Filtering blebs with various types of glaucoma were examined using Stratus OCT. Success rates were defined as intraocular pressure (IOP) (less-than or equal to) 15 mmHg and IOP reduction (greater-than or equal to) 25% without medication or additional surgery. Success rates among classified groups were compared using Kaplan-Meier survival curves and the log-rank test. Results: Blebs were classified into three different categories on the basis of the following Stratus OCT patterns: cystoid type (multiple cysts inside the bleb; 17 eyes), diffuse type (low to high reflective areas that were mixed inside the bleb; 31 eyes) and layer type (medium to high reflective layer inside the bleb; 24 eyes). Success rates in the cystoid-, diffuse- and layer-type blebs were 94%, 97% and 75% (P = 0.02), respectively. Conclusion: In trabeculectomy with MMC and a fornix-based conjunctival flap, there is a significant association between the success rates and the postoperative Stratus OCT findings of filtering blebs. ( Acta Ophthalmol.
K. Hirooka. Department of Ophthalmology, Kagawa University, Faculty of Medicine, 1750-1 Ikenobe, Miki, Kagawa 761-0793, Japan. kazuyk@med.kagawa-u.ac.jp
Classification:
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
