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Abstract #25801 Published in IGR 12-2
Early diagnosis of primary open-angle glaucoma in patients with high myopia after laser in situ keratomileusis
Zeng J; Guo H-K; Cui Y; Xie W-J; Li Z-M; Liao W-XChinese Ophthalmic Research 2010; 28: 441-444
Background: Laser in situ keratomileusis (LASIK) have been proved to be effective for refractive error eye. However, its safety and stability in high myopia eye is still a controversy. Clinically, one of reasons of regression after LASIK is primary open-angle glaucoma. Objective: The present study was to discuss the early diagnosis of primary open-angle glaucoma in patients with high myopia after LASIK. Methods: The clinical data was retrospectively analyzed from 25 eyes of 13 patients with high myopia received LASIK. The regression occurred after 2 years following the LASIK. Visual acuity, diopter, Orbscan, aberration, contrast sensitivity, intraocular pressure (Goldman IOP), optic axis, visual field and OCT were examined before and after LASIK. Primary glaucoma was diagnosed based on the criteria of National Glaucoma Group. Written informed consent was obtained from each patient before operation. Results: Refraction regression occurred in 23 eyes of 12 patients with the average regression equivalent (-1.57 (plus or minus) 0.36) D. The average uncorrected visual acuity was (0.42 (plus or minus) 0.14). Two eyes of 1 patient appeared the glaring symptom with the diameter of pupil 4-4.5 mm at daytime and 5.8-6.0 mm at night. Twelve eyes of 6 cases presented the post-correct IOP 21-26 mmHg with the thinner nerve fiber layer and glaucomatous visual field alteration. The other causes of regression included suspect glaucoma in 5 eyes of 3 patients and asthenopia in 8 eyes of 4 patients. Conclusion: The eyes received LASIK for high myopia is likely to occur refraction regression or dazzling, especially in 2-year duration after LASIK. Concurrent primary open-angle glaucoma may be one of reasons of regression. The glaucoma excluding test should be performed in the patients with refractive regression after LASIK.
J. Zeng. Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangzhou 510080, China. zj1969112@sina.com
Classification:
8.4 Refractive surgical procedures (Part of: 8 Refractive errors in relation to glaucoma)
8.1 Myopia (Part of: 8 Refractive errors in relation to glaucoma)