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Abstract #26070 Published in IGR 12-2
The distribution of intraocular pressure and its association with metabolic syndrome in a community
Park S-S; Lee E-H; Jargal G; Paek D; Cho S-IJournal of Preventive Medicine and Public Health 2010; 43: 125-130
Objectives: The current study was performed to assess the distribution of intraocular pressure (IOP) and its association with metabolic syndrome (MS) in a community. Methods: We measured IOP and MS components from 446 adults, age 20 or more years old, who reside in a community in Kyunggi Province, South Korea. We compared the level of IOP according to the number of metabolic abnormalities and between normal and abnormal metabolic components. Linear regression analyses were used to determine the relationship between IOP and metabolic components. Results: No significant difference in IOP (mean(plus or minus)SE) was found between men (12.24 (plus or minus) 2.42) and women (12.55 (plus or minus) 2.41 mmHg, p > 0.1), while IOP of men tended to decrease as age Increased (p for trend<0.01). After adjusting for age, IOP of subjects with abdominal obesity in men and high blood pressure in women were significantly higher than those without abdominal obesity or high blood pressure (p < 0.05). Female subjects with MS showed significantly higher IOP than those without MS. Participants with more metabolic disturbances tended to have a greater IOP elevation with a linear trend after adjusting for age and sex. In the univariate regression analysis, age and waist circumference were significantly associated with IOP in men, but systolic and diastolic blood pressure were associated with IOP in women. In final multiple regression model, age, systolic blood pressure, and triglyceride were associated with IOP in women, and age in men. Conclusions: These findings suggest that MS and its components may be important determinants of elevated IOP.
S.-I. Cho. 28 Yeongeon-dong, Jongnogu, Seoul, South Korea. scho@snu.ac.kr
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)