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Abstract #26131 Published in IGR 12-2
Target intraocular pressure for stability of visual field loss progression in normal-tension glaucoma
Aoyama A; Ishida K; Sawada A; Yamamoto TJapanese Journal of Ophthalmology 2010; 54: 117-123
PURPOSE: To determine the target intraocular pressure (IOP) level in normal-tension glaucoma (NTG) for visual field (VF) stability following trabeculectomy. METHODS: Forty eyes of 40 patients who underwent trabeculectomy were enrolled in this study. Progression was determined by a decrease in the Advanced Glaucoma Intervention Study VF defect score of four or more points. The Kaplan-Meier life table method was employed to compare the postoperative VF stability with predetermined IOP levels. RESULTS: The mean postoperative follow-up period was 12 years. At the final visit, the IOP was reduced from 15.2 to 9.4 mmHg on average (P < 0.0001). Reductions in IOP of 20% from baseline were achieved in 70.0% of eyes. The cumulative probability of VF stability was 92.7% in patients having an IOP reduction of >20%, whereas all patients in the poorly controlled IOP group showed progression (P < 0.0001). When IOP values of 9, 10, 11, and 12 mmHg were employed as the cutoff, the best VF prognosis was attained in eyes with a postoperative IOP of 10 mmHg. CONCLUSIONS: An IOP reduction of at least 20% from baseline or IOP Department of Ophthalmology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan. 6.20 Progression (Part of: 6 Clinical examination methods)Classification:
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
