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Abstract #26260 Published in IGR 12-2
Patterns of progression of localized retinal nerve fibre layer defect on red-free fundus photographs in normal-tension glaucoma
Suh MH; Kim DM; Kim YK; Kim TW; Park KHEye 2010; 24: 857-863
See also comment(s) by Anja Tuulonen •
PURPOSES: To investigate patterns of progression of localized retinal nerve fibre layer (RNFL) defect on red-free fundus photographs and to quantify extents of progression in normal-tension glaucoma (NTG) patients. METHODS: Sixty-five eyes of consecutive 65 NTG patients who had shown progression of localized RNFL defect on serial red-free fundus photographs were selected for this study. Patterns of progression of localized RNFL defect on red-free fundus photographs were categorized and extents of progression were quantified. Serial assessments of disc stereophotographs and visual fields were also performed to detect progression. RESULTS: The most common pattern of progression was widening of the defect towards the macula (n=37; 56.9%) followed by deepening of the defect (n=25; 38.5%), appearance of a new defect (n=6; 9.2%), and widening of the defect away from the macula (n=5; 7.7%). Eight eyes simultaneously showed two patterns of progression. Mean angular widening of the defect towards the macula and away from the macula was 6.4+/-4.1 degrees (range: 1.1-17.1 degrees , n=37) and 3.4+/-2.1 degrees (range: 1.1-5.2 degrees , n=5), respectively. No progression was observed on the disc stereophotographs (n=65) or in the visual fields (n=55) in 64 eyes (98.5%) and 46 eyes (83.6%), respectively. CONCLUSIONS: There were four patterns of progression of localized RNFL defect. In most cases, RNFL loss proceeded temporally.
Department of Ophthalmology, Seoul National University Hospital, Chongno-Gu, Seoul, Korea.
Classification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
6.20 Progression (Part of: 6 Clinical examination methods)
