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Abstract #26410 Published in IGR 12-3
Intraocular pressure and related systemic and ocular biometric factors in a population-based study in Japan: The kumejima study
Tomoyose E; Higa A; Sakai H; Sawaguchi S; Iwase A; Tomidokoro A; Amano S; Araie MAmerican Journal of Ophthalmology 2010; 150: 279-286
Purpose: To examine the distribution of intraocular pressure (IOP) and its related systemic and ocular biometric factors in a population-based study in a southwestern island of Japan. Design: Cross-sectional, population-based study. Methods: All residents of Kumejima Island, Japan, located in southwestern Japan (eastern longitude, 126 degrees 48 minutes and northern latitude 26 degrees 20 minutes), 40 years of age and older were asked to undergo a comprehensive questionnaire and ocular examination, including measurement of IOP with Goldmann applanation tonometry. Results: Of the 4632 eligible residents, 3762 (81.2%) underwent the examination. In 2838 nonglaucomatous subjects from whom reliable measurements of IOP were obtained, the mean IOPs (plus or minus) standard deviation in all, men, and women were 15.1 (plus or minus) 3.1 mm Hg (n = 2838), 15.2 (plus or minus) 3.1 mm Hg (n = 1450), and 15.1 (plus or minus) 3.0 mm Hg (n = 1388), respectively, with no significant intersex difference (P = .63). Multivariate regression analysis demonstrated that higher IOP was significantly correlated with younger age (P < .001), higher body mass index (P < .001), higher systolic blood pressure (P < .001), history of diabetes mellitus (P = .001), thicker central corneal thickness (P < .001), steeper corneal curvature (P < .001), and longer axial length (P < .018), but not with anterior chamber depth and the Shaffer angle width grade. Conclusions: Younger age, higher body mass index, higher systolic blood pressure, diabetes, thicker central corneal thickness, and steeper corneal curvature were significantly correlated with higher IOP. The present results confirm that IOP is associated with systemic and ocular biometric factors and may define specific subgroups most likely to have an elevated IOP.
S. Amano. 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. amanos-tky@umin.ac.jp
Classification:
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
1.1 Epidemiology (Part of: 1 General aspects)
