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Abstract #26633 Published in IGR 12-3

Intraocular pressure and ocular pulse amplitude using dynamic contour tonometry in Chinese normal subjects

Fang Y; Pan Y-Z; Qiao R-H; Li M; Cai Y; Liu L-N
Chinese Ophthalmic Research 2010; 28: 550-554


Background: The measurement of intraocular pressure (IOP) plays an important role in diagnosis and treatment of glaucoma. Dynamic contour tonometry (DCT) is a newly device. Theoretically, it can overcome the shortcomings of Goldmann applanation tonometry (GAT). Objective This study was to survey the application of DCT and compare with GAT. Methods: The IOP was measured with DCT and GAT in 60 eyes of 60 normal Chinese subjects. Some parameters including ocular pulse amplitude (OPA), central corneal thickness (CCT), corneal curvature (CCV), anterior chamber depth (AC) and axial length (AL) were obtained with ultrasonic pachymeter and A-scan unit. The correlation of DCT or GAT with CCT, CCV, AC, AL, systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were calculated to evaluate the influent factors for IOP by DCT or GAT. This study was authorized by Ethics Committee of Peking University First Hospital. Written informed consent was obtained from each subject in initial procedure of this study. Results: The mean IOP of DCT and GAT were (16.04 (plus or minus) 2.57) mmHg and (14.20 (plus or minus) 2.93) mmHg, respectively, showing that the IOP by GAT was higher than that by DCT (t = 6.454, P < 0.01). The Pearson correlation analysis showed the significantly positive correlation between DCT IOP with GAT IOP (r = 0. 684, P < 0.01). No significant correlation was found between DCT IOP with CCT, CCV, AC and AL (P > 0.05). The positive correlation was revealed between GAT IOP with CCT (r = 0.291, P = 0.024). The mean OPA (2.50 (plus or minus) 0.89) mmHg was positive correlated with CCV (r = 0.343, P = 0.007), but no remarkable correlation was seen between OPA with DCT, CCT, SBP, DBP and HR(P > 0.05). Conclusion: The IOP by DCT method has a good correlation with that by GAT. CCT, CCV and AL have no influence to the IOP by DCT. OPA is influenced by CCV rather than DCT, CCT, SBP, DBP and HR in normal subjects.LA: Chinese

Y. Fang. Department of Ophthalmology of Peking, University First Hospital, Beijing 100034, China.


Classification:

6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)



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