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Abstract #26654 Published in IGR 12-3
Modified visual field trend analysis
De Moraes CGV; Ritch R; Tello C; Liebmann JMJournal of Glaucoma 2010;
PURPOSE: Visual field trend analysis can be influenced by outlying values that may disproportionately affect estimation of the rate of change. We tested a modified approach to visual field trend analysis to minimize this problem. METHODS: Automated pointwise linear regression (PLR) was used in glaucoma patients with (greater-than or equal to)13 SITA-Standard 24-2 VF tests in either eye. In the control group (Group A), conventional PLR using the entire set of VF tests was carried out. In the other 3 groups (study groups), a truncated analysis was done using only the first and last 3 (Group B), first and last 4 (Group C), or first and last 5 (Group D) VF tests. We compared the global slopes (dB/y), number of eyes experiencing significant progression, and significant improvement between groups. RESULTS: Ninety eyes of 90 patients were evaluated. The mean number(plus or minus)SD of VF tests was 15.7(plus or minus)2.6, spanning 7.8(plus or minus)1.7 years. The study groups showed similar global rates of VF change as the control group (Group A=-0.48(plus or minus)0.5, Group B=-0.48(plus or minus)0.6, Group C=-0.48(plus or minus)0.6, Group D=-0.48(plus or minus)0.5 dB/y, P>0.05), and a similar number of eyes reaching a progression endpoint (Group A=53, Group B=52, Group C=49, Group D=53, P>0.05). However, Group B showed fewer eyes presenting VF improvement (false-positives). CONCLUSIONS: The modified VF trend-analysis showed greater specificity than conventional PLR in a population with glaucoma.
C. G. V. de Moraes.
Classification:
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.20 Progression (Part of: 6 Clinical examination methods)
