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Abstract #26725 Published in IGR 12-3

Quantitative assessment of anterior chamber parameters in pigmentary glaucoma using slit-lamp optical coherence tomography

Dinc UA; Kulacoglu DN; Oncel B; Yalvac IS
European Journal of Ophthalmology 2010; 20: 702-707

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PURPOSE. To quantitatively assess the parameters of anterior chamber and angle dimensions by slit-lamp optical coherence tomography (SL-OCT) in eyes with pigmentary glaucoma (PG). METHODS. A total of 18 eyes of 11 patients with PG and 18 eyes of 11 healthy volunteers were included in the study. Anterior chamber depth (ACD), anterior chamber volume (ACV), spur distance (internal horizontal anterior chamber diameter), central corneal thickness (CCT), angle opening distance at 500 (mu)m from the scleral spur (AOD 500), and trabecular iris space area at 500 (mu)m from the scleral spur (TISA 500) parameters were detected by SL-OCT. The differences of anterior chamber parameters between patients with PG and the control group were analyzed by Mann-Whitney U test. RESULTS. Mean ACD and ACV were measured as 3.28(plus or minus)0.38 mm and 191.6(plus or minus)39.7 mm(3) respectively in the PG group. Mean AOD 500 and TISA 500 were 0.88(plus or minus)0.47 mm and 0.29(plus or minus)0.15 mm(2) at the nasal angle and 1.14(plus or minus)0.67 mm and 0.41(plus or minus)0.23 mm(2) at the temporal angle, respectively. Nasal and temporal angles were 49.83(plus or minus)11.1(degrees) and 53.83(plus or minus)10.46(degrees). In eyes with PG, the midperipheral iris configuration was found to be considerably concave in 15 eyes (83.3%). Except CCT and spur distance, all anterior chamber dimension and angle parameters detected by SL-OCT were found to be significantly higher in the eyes with PG (Mann-Whitney U test, p<0.05). CONCLUSIONS. SL-OCT provided highly quantitative data on the parameters of anterior chamber and angle dimensions in PG. The evaluation of the anterior segment anatomy using SL-OCT revealed increased anterior chamber dimensions and posterior bowing of the iris consistent with the increase in angle parameters in patients with PG.

U. A. Dinc. Department of Ophthalmology, Yeditepe University, Eye Hospital, Sakir Kesebir Sokak No:28 Balmumcu, Besiktas, 34349 Istanbul, Turkey. umutdinc@yahoo.com

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Classification:

9.4.3.1 Pigmentary glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.3 Glaucomas associated with disorders of the iris and ciliary body)
6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)

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