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Abstract #26776 Published in IGR 12-3
Hypertension and glaucoma: A population-based study
Finkelstein J; Cha EJournal of Clinical Hypertension 2010; 12: A132
Objective: To investigate the prevalence and association of hypertension and glaucoma in US adult population. Background: Glaucoma is a complicated disease in which damage to the optic nerves results in vision loss. A limited number of studies explored the relationship between the systemic hypertension and glaucoma in case reports. Population-based studies are needed to estimate the prevalence and association between hypertension and glaucoma. Methods: The study sample of 8,023 hypertension and 722 glaucoma patients was drawn from the Sample Adult File of the National Health Interview Survey (NHIS) for year 2002. Hypertension was defined by the question, nullHave you ever been told by a doctor or other health professional that you had hypertension?null Glaucoma was defined by a similar question. Subjects who nullRefusednull or answered nullNot ascertainednull or 'Don't know' were excluded from the study sample. Population-based prevalence and multiple logistic regression were carried out to analyze the association between hypertension and glaucoma. Logistic regression model was adjusted by socio-demographic variables including age, gender, race, marital status, education, and poverty income ratio (PIR). The analysis employed NHIS sampling weights to generate data representative of the entire US population. Statistical analyses were conducted by SAS version 9.0. Results: In US general population 24.3% and 2% reported to have hypertension and glaucoma respectively. Among hypertension patients 4.9% had glaucoma compared to 1.1% of general population. While controlling for age, gender, race, marital status, education, and poverty income ratio (PIR), individuals with hypertension showed 1.7 times (95% CI 1.34-2.11, p<0.0001) higher risk of having glaucoma with statistical significance. The risk of glaucoma was elevated among Non-Hispanic Blacks as well with odd ratio of 1.7 (p=0.004). Conclusion: Overall, the individuals with hypertension showed 1.7 times increased risk of having glaucoma as compared to the general population without hypertension.
J. Finkelstein. School of Medicine, Johns Hopkins University, BaltimoreUnited States.
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
