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Abstract #26831 Published in IGR 12-3
Increase of intraocular pressure after Nd: YAG laser iridectomy interruped by pilocarpine
Wang C-Y; Ai Y-D; Tao G-TInternational Journal of Ophthalmology 2010; 10: 1561-1563
AIM: To investigate if pilocarpine can effectively prevent the acute increase of intraocular pressure (IOP) in brown eyes after Nd: YAG laser iridectomy. METHODS: Totally 48 cases 58 eyes with primary angle-closure glaucoma were divided into treatment and control groups, which were matched by age and sex. One drop of pilocarpine was applied into the conjunctival sac at one hour before laser iridectomy and immediately after laser iridectomy in treatment group, whereas one drop of antibiotic as placebo was applied in control group at the same time. IOP, pupil diameter were measured at 0.5, 1.0, 1.5, 2.0, 3.5 hours after laser iridectomy. RESULTS: The maximum increase of IOP after laser iridectomy was 0.62 (plus or minus) 0.67kPa and 1.13 (plus or minus) 0.87kPa in treatment and control group respectively, there was a significant difference (P = 0.03). The obvious decrease of IOP occurred at 0.5, 1.0 and 1.5 hours after laser iridectomy in treatment group. No ocular and systemic side effects were found in treatment group, except pupil diameter was obviously larger in treatment group than that in control group. CONCLUSION: 20g/L pilocarpine can effectively prevent the acute increase of IOP in brown eyes after Nd: YAG laser iridectomy.LA: Chinese
C.-Y. Wang. Department of Ophthalmology, Inner Mongolia Medical College, Hohhot 010050, China. zxdwchy8495@sina.com
Classification:
12.2 Laser iridotomy (Part of: 12 Surgical treatment)
11.2 Cholinergic drugs (Part of: 11 Medical treatment)