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Abstract #26978 Published in IGR 12-4
Intraocular pressure measurements after corneal collagen crosslinking with riboflavin and ultraviolet A in eyes with keratoconus.
Kymionis GD; Grentzelos MA; Kounis GA; Portaliou DM; Detorakis ET; Magarakis M; Karampatakis VE; Pallikaris IGJournal of Cataract and Refractive Surgery 2010; 36: 1724-1727
PURPOSE: To determine the possible effect of corneal collagen crosslinking (CXL) with riboflavin and ultraviolet A (UVA) on intraocular pressure (IOP) measurements by Goldmann applanation tonometry (GAT). SETTING: Institute of Vision and Optics, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece. DESIGN: Prospective case series. METHODS: This noncomparative study measured IOP by GAT before CXL and 6 months and 12 months after CXL. RESULTS: The study evaluated 55 eyes (55 patients). There was a statistically significant increase in the measured IOP 6 months and 12 months after CXL (both P<.001). The mean measured IOP was 9.95 mm Hg ± 3.01 (SD) before CXL, 11.40 ± 2.89 mm Hg at 6 months, and 11.35 ± 3.38 mm Hg at 12 months. The change in IOP measurements at both postoperative examinations was not correlated with patient age, preoperative pachymetry, or preoperative keratometry readings. CONCLUSION: After riboflavin-UVA CXL in eyes with keratoconus, there was a significant increase in IOP measured by GAT that was probably caused by an increase in corneal rigidity.
Institute of Vision and Optics, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.
Classification:
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
