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Abstract #27128 Published in IGR 12-4
Primary open angle glaucoma and intraocular pressure in patients with systemic hypertension
Onakoya AO; Ajuluchukwu JN; Alimi HLEast African Medical Journal 2009; 86: 74-78
Objective: To investigate the association between Primary Open Angle Glaucoma (POAG), Intraocular Pressure (IOP) and systemic hypertension. Design: Cross-sectional, convenient and controlled study. Setting: Eye Clinic of the Lagos University Teaching hospital, Idi-Araba, Lagos, Nigeria. Subjects: Consecutive new patients with documented history of hypertension medication of over three months and current attendees at hypertension clinic of the same hospital were enrolled into the study. Results: A total of 150 hypertensive patients and 50 age-sex matched controls were studied. Age range of hypertensives was 34-54 years and controls 31-71 years. The mean age for hypertensive group was 56 years ((plus or minus)12.95) and controls 54.76 years ((plus or minus)9.65) p>0.1. The mean IOP was 28.45mmHg ((plus or minus)10.3) in hypertensive group and 15.2mmHg ((plus or minus)5.09) in controls (P<0.001). POAG was present in 58 (38.7%) of the hypertensive patients whilst only nine (18.0%) had POAG in control group (p<0.01 odds ratio: 22). IOP> 21mmHg was found in 28 (18.7)) of hypertensive group and two (4.0%) of the control (p<0.01 odds ratio 4.7). Conclusion: Systemic hypertension showed a modest positive association with elevated intraocular pressure. The strong relationship with IOP in part supports the association with POAG.
A. O. Onakoya. Guinness Eye Centre, Lagos University Teaching Hospital, University of Lagos, Idi-Araba, PMB 12003, Lagos, Nigeria.
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
