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Abstract #27260 Published in IGR 12-4
Pseudoexfoliation syndrome and glaucoma
Blagoeva H; Balabanov Ch; Petrov DActa Medica Bulgarica 2010; 37: 12-21
The aim of this study is to describe the epidemiological characteristics, physical findings and morphological signs of pseudoexfoliative glaucoma. This is a prospective, observational case-control study, which includes a 7-year period of observation of 893 patients (1786 eyes) with Pseudoexfoliation glaucoma (PeG) and 52 patients with Primary Open Angle Glaucoma (POAG). Color Doppler Ultrasonogrphy (CDU) of carotid and ophthalmic artery of 18 eyes with PeG was performed. Peak systolic and end diastolic velocities were measured. Mean flow velocities, resistive and pulsative indices were calculated. Transmission electron microscopic (TEM) study of 24 eyes with PeG and 12 eyes with POAG was performed. Specimens from conjunctiva, trabecular meshwork and iris were obtained during surgery. The results show high prevalence of PeG (37,19% of all glaucoma types). The patients were predominantly men and the recessive type of inheritance was proposed. PeG was diagnosed more frequently in elderly (60-80 years). CDU showed that the hemodynamic parameters were altered. It was observed by TEM that all cell types are involved in the pathological process.
H. Blagoeva. St.Sofia Hospital, 104 Bulgaria str., Sofia, Bulgaria. ch_blagoeva@abv.bg
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
