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Abstract #27358 Published in IGR 12-4
Evaluation of biological measurement of ocular anterior segment in patients with primary angle closure glaucoma with cataract
Cao C-L; Xue C-Y; Li J-JChinese Ophthalmic Research 2010; 28: 979-983
Background: Eyes that are predisposed to primary angle closure usually have a shallow anterior chamber. Phacoemulsification for primary closed-angle glaucoma complicated with cataract may have a good outcome on these eyes. Objective: Anterior eye segment in patients with primary angle closure glaucoma associated with cataract was studied using high-speed slit lamp OCT(SL-OCT), ultrasound biomicroscope (UBM), and A-ultrasound. This study was to perform the biological measurement of the anterior eye segment in order to determine the timing of cataract phacoemulsification. Methods: This is a diagnostic test. Phacoemulsification and intraocular lens implantation was performed in 42 eyes of 30 patients with primary angle closure glaucoma associated with cataract. The changes of ocular anterior segment, including periphery, mid-periphery and pupil edge areas were examined using SL-OCT, UBM, and A-ultrasound before and one month after the surgery respectively. The visual acuity and intraocular pressure(IOP) were recorded preoperatively and postoperatively. The measured outcomes of ocular anterior segment structure by SL-OCT, UBM and A-ultrasound were compared. Oral informed consent was obtained from the all patients prior to the medical examination. Results: The anterior chamber depth (ACD), distance of 500 (mu)m from the scleral spur (AOD(500)) and trabecular iris angle obtained by SL-OCT or UBM were significantly increased 1 month after surgery, showing statistically significant differences in comparison with before surgery (t = - 15.695, P < 0.01; t = -17.124, P < 0.01; t = - 12.255, P < 0.01). No significant differences were found in the iris thickness(IT) before and after surgery by SL-OCT or UBM (P > 0.05). The ACD value measured by SL-OCT was higher in comparison with that by OCT and UBM before surgery (F = 21.060, P = 0.000) and after surgery (F = 21.012, P = 0.000). The differences of IOP and visual acuity between before and after surgery were statistically significant (F = 35.792, P = 0.000; F = 124.891, P = 0. 000). Conclusion: SL-OCT, UBM and A-ultrasound all provide the objective and accurate parameters of the anterior eye segment for the patients with primary open-angle glaucoma with cataract. Phacoemulsification with intraocular lens implantation can prevent and control high IOP. LA: Chinese
C.-L. Cao. Department of Ophthalmology, Nanjing General Hospital, Nanjing Military Command, Nanjing 210002, China. xuechunyancn@163.com
Classification:
6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)
9.3.5 Primary angle closure (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
9.4.4.2 Glaucomas associated with cataracts (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
