advertisement
Abstract #27497 Published in IGR 12-4
Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
El Mallah MK; Walsh MM; Stinnett SS; Asrani SGClinical Ophthalmology 2010; 4: 889-893
Purpose: To evaluate the effect of selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG) patients. Patients and methods: A retrospective review was performed of NTG patients who had undergone SLT at the Duke University Eye Center between 12/2002 and 7/2005. For each eye of each patient at pre-laser and post-laser time points, the IOP measurements were summarized by mean, standard deviation, and range. Then for each of these descriptive statistics, the differences between pre-laser and post-laser values were obtained. Statistical analysis was performed using a random effects model. Main outcome measures: difference in mean IOP, standard deviation of IOP, and range of IOP. Results: Thirty-one eyes of 18 patients were included for analysis. The average of the mean pre-operative IOP measurements was 14.3 (plus or minus) 2.6 mmHg compared to 12.2 (plus or minus) 1.7 mmHg (P < 0.001) post-operatively. The mean pre-operative standard deviation was 1.9 (plus or minus) 0.9 mmHg compared to 1.0 (plus or minus) 0.6 mmHg (P = 0.002) post-operatively while the mean IOP range prior to treatment was 4.5 (plus or minus) 2.5 mmHg compared to 2.5 (plus or minus) 1.9 mmHg (P = 0.017) after treatment. Conclusion: In this pilot study, SLT was found to lower mean IOP and intervisit IOP variation in NTG patients. Given the importance of IOP variation and its association with glaucoma progression, measurement of IOP variation following treatment with SLT may be considered. (copyright) 2010 El Mallah et al, publisher and licensee Dove Medical Press Ltd.
M. K. El Mallah. Ocala Eye, 1500 SE Magnolia Ext, Suite 106, Ocala, FL 34471, United States. elmallah@post.harvard.edu
Classification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)
6.1.2 Fluctuation, circadian rhythms (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
