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Abstract #27504 Published in IGR 12-4
Central corneal thickness and intraocular pressure in the cameroonian nonglaucomatous population
Eballe AO; Koki G; Ellong A; Owono D; Epee E; Bella LA; Mvogo CE; Kouam JMClinical Ophthalmology 2010; 4: 717-724
Aim: We performed a prospective, analytical study from 01 January to 31 March 2009 in the Ophthalmology Unit of the Gyneco-Obstetric and Pediatric Hospital of Yaounde, aiming to determine the profile of central corneal thickness (CCT) in the Cameroonian nonglaucomatous black population and its relationship with intraocular pressure (IOP). Results and discussion: Four hundred and eighty-five patients (970 eyes) meeting our inclusion criteria were selected for this study. The average CCT was 529.29 (plus or minus) 35.9 (mu)m in the right eye (95% confidence interval [CI]: 526.09-532.49), 528.19 (plus or minus) 35.9 (mu)m in the left eye (95% CI: 524.99-531.40) and 528.74 (plus or minus) 35.89 (mu)m in both eyes (95% CI: 526.48-531.00), range 440 to 670 (mu)m. The average IOP was 13.01 (plus or minus) 2.97 mmHg in both eyes (95% CI: 12.82-13.19). A rise in CCT by 100 (mu)m was followed by an increase in IOP of about 2.8 mmHg (95% CI: 2.3-3.6) for both eyes taken together. Linear regression analysis showed that corneal thickness was negatively correlated with age and IOP was positively related with age. Conclusion: CCT in the Cameroonian nonglaucomatous black population was found to be lower compared with CCT values in Caucasian and Asian populations. On the basis of reference values ranging between 527 and 560 (mu)m, an adjustment of IOP values by a correction factor is required for many Cameroonian patients. This will improve the diagnosis and follow-up of glaucoma by helping to detect true ocular hypertension.
A. O. Eballe. Department of Ophthalmology, Gyneco-Obstetric and Pediatric Hospital of Yaounde, PO Box 4362, Yaounde, Cameroon, United Kingdom. andyeballe@gmail.com
Classification:
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)