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Abstract #27509 Published in IGR 12-4

Crystallization after intravitreal ganciclovir injection

Choopong P; Tesavibul N; Rodanant N
Clinical Ophthalmology 2010; 4: 709-711

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Purpose: To report crystal formation as a complication of intravitreal ganciclovir injection. Patients and methods: A 73-year-old female patient with unilateral cytomegalovirus retinitis was treated with intravitreous ganciclovir (4 mg/0.04 mL). Results: After the intravitreal injection, sudden crystallization was observed in the vitreous humor. The patient experienced marked reduction in visual acuity and increased intraocular pressure. Despite aqueous paracenthesis and pars plana vitrectomy, optic atrophy was observed and her visual acuity remained unimproved after 12 months. Conclusion: Crystal formation can occur as a complication of intravitreal ganciclovir injection. Associated retinal and optic nerve damage was found which results in permanent visual morbidity. (copyright) 2010 2010 Choopong et al, publisher and licensee Dove Medical Press Ltd.

P. Choopong. Department of Ophthalmology, Siriraj Hospital, Mahidol University, 2 Prannok Road, Prannok, Bangkok Noi, Bangkok 10200, Thailand. pitipol@hotmail.com

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Classification:

9.4.11.5 Glaucomas associated with vitreoretinal surgery (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.11 Glaucomas following intraocular surgery)

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