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Abstract #27555 Published in IGR 12-4
New devices for dispensing ophthalmic treatments may be the key to managing the life cycles of established products
Birkhoff M; Marx DDrug Delivery Technology 2010; 10: 16-21
The new ophthalmic devices of Aptar Pharma solve major current issues with ophthalmic multidose devices. They are suited to many liquid ophthalmic medications, in particular those for chronic conditions such as glaucoma or dry eye; and the simple intuitive handling is ideal for the target group. Preservatives can be omitted, which will be appreciated by the high number of patients experiencing eye irritation or allergic responses with preserved formulations. This positive benefit for patients is most likely going to increase medication compliance as prescribed. The new devices also offer advantages to the manufacturers of ophthalmic medications as there is no need for preservatives in the formulation that could potentially interact with other components of the formulation or the device, and the development and (later on) production process is less difficult. For the manufacturing of the OSD and ODD, substantially less material is used compared to that needed to pack the same number of doses with blow-fill-seal technology. The new devices can provide cutting edge technology for the life-cycle management of established products with low investments in filling technology.
M. Birkhoff. Aptar Pharma, .
Classification:
11.16 Vehicles, delivery systems, pharmacokinetics, formulation (Part of: 11 Medical treatment)
11.17 Cooperation with medical therapy e.g. persistency, compliance, adherence (Part of: 11 Medical treatment)
